Sucralose is a popular artificial sweetener that is used in a wide variety of food and beverage products. It is commonly found in diet sodas, sugar-free desserts, and other low-calorie foods. Sucralose has been approved for use by regulatory agencies around the world, including the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). These agencies have conducted extensive reviews of the scientific research on sucralose and have determined that it is safe for consumption at recommended levels.

One of the key studies that supports the safety of sucralose is a two-year feeding study conducted by the National Toxicology Program (NTP). In this study, rats were fed high doses of sucralose for two years, and no adverse effects were observed. Based on the results of this study and other research, the FDA concluded that sucralose is safe for human consumption.

Another important study that supports the safety of sucralose is a review conducted by the EFSA. The EFSA reviewed the scientific literature on sucralose and concluded that it does not pose a risk to human health at current levels of exposure. The EFSA established an Acceptable Daily Intake (ADI) for sucralose, which is the amount that can be consumed daily over a lifetime without any adverse effects.

In addition to these regulatory reviews, numerous scientific studies have been conducted on the safety of sucralose. These studies have looked at a wide range of potential health effects, including its impact on weight management, blood glucose levels, and gut health. Overall, the majority of studies have found that sucralose is safe for human consumption.

One study published in the Journal of Toxicology and Environmental Health examined the effects of sucralose on body weight and food intake in rats. The researchers found that sucralose did not have any significant impact on body weight or food intake, even when consumed at high doses. This suggests that sucralose is unlikely to contribute to weight gain or overeating in humans.

Another study published in the Journal of Food and Chemical Toxicology looked at the effects of sucralose on blood glucose levels in healthy adults. The researchers found that sucralose did not have any significant effect on blood glucose levels, indicating that it can be safely consumed by individuals with diabetes or prediabetes.

Overall, the scientific research supports the safety of sucralose as an artificial sweetener. Regulatory agencies around the world have determined that sucralose is safe for human consumption at recommended levels, and numerous studies have found no adverse health effects associated with its use. As with any food ingredient, it is important to consume sucralose in moderation as part of a balanced diet.